Management of Chronic Abdominal Distension and Bloating
نویسندگان
چکیده
Abdominal bloating and distension are 2 of the most commonly reported gastrointestinal symptoms. is characterized by symptoms trapped gas, abdominal pressure, fullness. defined as a measurable increase in girth. These frequently co-exist, although they can occur separately. Defined Rome IV criteria, functional coincide with other disorders, such dyspepsia, irritable bowel syndrome, constipation. develop for multiple reasons, including food intolerances, previous infection that perturbed intestinal microbiota, disordered visceral sensation, delayed transit, or an abnormal viscero-somatic reflux. Treatment be challenging to patients providers—no regimen has been consistently successful. Successful treatment involves identifying etiology, assessing severity, educating reassuring patients, setting expectations. Therapeutic options include dietary changes, probiotics, antibiotics, prokinetic agents, antispasmodics, neuromodulators, biofeedback. We review epidemiology effects chronic pathophysiology, discuss appropriate diagnostic strategies, assess available options. Nearly all population felt, at one time another, gassy, bloated, distended. For many, these transient sensations after eating, resolve spontaneously, do not lead medical consultation. others, however, chronic, bothersome, negatively affect daily life. The prevalence substantial, ranging from 16% 31% general population, high 66%–90% syndrome (IBS).1Drossman D.A. Li Z. Andruzzi E. et al.U.S. householder survey disorders. Prevalence, sociodemography, health impact.Dig Dis Sci. 1993; 38: 1569-1580Crossref PubMed Scopus (1723) Google Scholar, 2Sandler R.S. Stewart W.F. Liberman J.N. al.Abdominal pain, diarrhea United States: 2000; 45: 1166-1171Crossref (0) 3Schmulson M. Ortiz O. Santiago-Lomeli al.Frequency disorders among healthy volunteers Mexico City.Dig 2006; 24: 342-347Crossref (57) 4Zuckerman M.J. Nguyen G. 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Impaired transit tolerance gas 14-19Crossref (274) may diagnosed criteria (see Table 1).7Lacy Of note, neither required present patient meet both noted supporting criteria.Table 1Functional Bloating Distension7Lacy ScholarDiagnostic and/or include:-Recurrent occurring least 1 d/wk average;-Bloating should predominant symptom;-Patients constipation, diarrhea, postprandial distress syndrome;-Symptom onset occurred 6 months prior diagnosis;-Symptoms active within preceding 3 months. Open table new tab etiology complex, often multifactorial incompletely understood. differential diagnosis includes organic 2). Most believe due increased amount “gas” (GI) tract, this accounts minority patients. Normal production, absorption, excretion illustrated Figure 1. Computed tomography (CT) imaging luminal 25% (FGIDs) spontaneous episode following consumption “high-flatulence” diet.14Benduzú R.A. Barba Burri al.Intestinal content distribution gut symptoms.Neurogastroenterol Motil. 2015; 27: 1249-1257Crossref (16) sections highlight major pathophysiologic causes 2).Table 2Common Causes Chronic DistensionOrganic/pathologic etiologies-Small bacterial overgrowth-Lactose, fructose, carbohydrate intolerances-Celiac disease-Pancreatic insufficiency-Prior gastroesophageal surgery (eg, fundoplication, bariatric surgery)-Gastric outlet obstruction-Gastroparesis-Ascites-Gastrointestinal gynecologic malignancy-Hypothyroidism-Adiposity-Small intestine diverticulosis-Chronic pseudo-obstructionDisorders gut-brain interaction-Irritable syndrome-Chronic idiopathic constipation-Pelvic floor dysfunction-Functional dyspepsia-Functional 2Pathophysiology bloating.View Large Image ViewerDownload Hi-res image Download (PPT) Small overgrowth (SIBO) lactose fructose) intolerance common Excess small bacteria fermentation subsequent production stretch intestine. Altered viscerosomatic reflex play role mechanisms studied SIBO. Carbohydrate osmotic load, excess fluid retention, colon. lack consensus regarding ideal test diagnose SIBO makes it difficult ascertain its true prevalence. In addition, no prospective trial evaluated solely determine data come best-studied FGID, IBS. A meta-analysis 0%–20% control subjects vs 4%–78% IBS.15Grace Shaw C. Whelan K. al.Review article: – prevalence, features, current developing tests, treatment.Aliment Pharmacol Ther. 2013; 674-688Crossref intolerance, similar symptoms, approaches 20%.16Lomer M.C.E. Review aetiology, diagnosis, mechanisms, evidence intolerance.Aliment 1: 262-275Crossref (49) unclear does necessarily correspond malabsorption breath test. symptomatic various FGIDs (n = 1372) identified 51% 32%, respectively, fructose 60% 45%, respectively.17Wilder-Smith C.H. Materna Wermelinger al.Fructose testing: relationship disorders.Aliment 37: 1074-1083Crossref (90) Lactase deficiency itself malabsorption, individuals who lactase-deficient become ingesting lactose. This indicates genetic predisposition, hypersensitivity) generation some No studies focused implications microbiome pathogenesis contrast, numerous described microbiota motility, permeability.18Shin Preidis G.A. Shulman R. al.The adult pediatric disorders.Clin 2019; 17: 256-274Abstract (26) Quantitative qualitative differences comparing subjects.19Kassinen Krogius-Kurikka Makivuokko fecal differs significantly subjects.Gastroenterology. 2007; 133: 24-33Abstract (689) Scholar,20Carroll I.M. Ringel-Kulka T. Y.H. al.Molecular analysis luminal- mucosal-associated diarrhea-predominant Physiol Gastrointest Liver Physiol. 2011; 301: G799-G807Crossref (176) significant reductions specific taxa members Ruminococcaceae Eubacteriaceae families compared subjects.21Ringa-Kulka Benson A.K. 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An elegant CT scan diaphragmatic descent relatively gas. comparison, marked resulting ascent.29Accarino Perez results caudo-ventral redistribution contents.Gastroenterology. 136: 1544-1551Abstract (77) Abdominophrenic dyspepsia (FD) bloating.30Burri Huaman J.W. al.Mechanisms dyspepsia.Gut. 2014; 63: 395-400Crossref (37) ScholarFigure 4Treatment algorithm asterisk (∗) refers anemia, bleeding, weight loss >10% body weight, family history GI malignancy. 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منابع مشابه
Management Strategies for Abdominal Bloating and Distension.
Bloating and distension are among the most common gastrointestinal complaints reported by patients with functional gut disorders and by the general population. These 2 complaints are also among the most prevalent of the severe symptoms reported by patients with irritable bowel syndrome. Nonetheless, only a limited number of published studies have specifically addressed bloating; it is infrequen...
متن کاملReview article: abdominal bloating and distension in functional gastrointestinal disorders--epidemiology and exploration of possible mechanisms.
BACKGROUND A sensation of abdominal bloating, sometimes accompanied by an increase in girth (distension), is one of the most common and most intrusive features of functional bowel disorders. AIM To conduct a systematic, evidence-based review of the epidemiology and pathophysiology of abdominal bloating and its relationship to distension. METHODS The terms bloating, distension, functional bo...
متن کاملTowards a better understanding of abdominal bloating and distension in functional gastrointestinal disorders.
Abdominal bloating is an extremely common symptom affecting up to 96% of patients with functional gastrointestinal disorders and even 30% of the general population. To date bloating has often been viewed as being synonymous with an actual increase in abdominal girth, but recent evidence suggests that this is not necessarily the case. This review examines the relationship between the symptom of ...
متن کاملAbdominal Bloating: Pathophysiology and Treatment
Abdominal bloating is a very common and troublesome symptom of all ages, but it has not been fully understood to date. Bloating is usually associated with functional gastrointestinal disorders or organic diseases, but it may also appear alone. The pathophysiology of bloating remains ambiguous, although some evidences support the potential mechanisms, including gut hypersensitivity, impaired gas...
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ژورنال
عنوان ژورنال: Clinical Gastroenterology and Hepatology
سال: 2021
ISSN: ['1542-7714', '1542-3565']
DOI: https://doi.org/10.1016/j.cgh.2020.03.056